Abstract: Objective: To improve the traditional method for refining snake venom serum and develop a new method for preparing snake venom serum with high yield, high purity, low cost, and easy preservation and use. The method first extracts IgG from anti snake venom serum and then enzymatically hy...
[Abstract] Objective: To evaluate the safety of hemocoagulase (HCA) from Agkistrodon acutus after minimally invasive percutaneous nephrolithotomy (MPCNL). Methods: 40 patients were selected, who were not given hemostatic drugs before and during the operation, and were continuously injected with H...
Objective To evaluate the hemostatic effect of Haemocoagulase from Agkistrodon acutus (HCA) in nasal endoscopic surgery. Method: Sixty patients who underwent elective endoscopic sinus surgery were randomly divided into an observation group (R group) and a control group (F group), with 30 patients...
The Snake Venom Research Institute of Guangxi Medical University was established in 1983 and is one of the well-known snake venom research centers in China. The research institute has strong technical strength, with a laboratory area of over 300 square meters and advanced instruments and equipmen...
Objective: To study the effect of tumor suppression component I (AAVC-I) on the proliferation inhibition and apoptosis of human lung cancer A549 cells. Methods: The MTT method was used to detect the 24h and 48h inhibition rates of A549 cells by AAVC-I at different concentrations.
HE staining and ...
Separation of anticoagulant and fibrinolytic components from Agkistrodon acutus venom and their effects on the coagulation system
Objective: To study the effect of purified thrombin like enzyme and plasmin from Agkistrodon acutus venom on blood coagulation system
Methods: Thrombin like enzyme and...
Separation of anticoagulant and fibrinolytic components from Agkistrodon acutus venom and their effects on the coagulation system
Objective: To study the effect of purified thrombin like enzyme and plasmin from Agkistrodon acutus venom on blood coagulation system
Methods: Thrombin like enzyme and...
[Abstract] This article reports that Agkistrodon acutus venom, Agkistrodon acutus venom, and anti snake venom serum can promote the vaccination of S_ (180). EAC ascites cancer mice significantly prolong survival time and reduce vaccination rates, but cannot completely prevent the growth of pain c...
Snake venom has many bioactive components, mainly including protease and polypeptide
It accounts for about 90%~95% of the dry weight of snake venom [l
With the continuous development of technology, many biological protein active ingredients in snake venom are gradually
It has been isolated and pu...
Objective To investigate the effect and phase of the component of Agkistrodon acutus venom ACTX-8 on the adhesion and invasion of cervical cancer cell Hela
Shutdown system. Methods Fibronectin was coated in 96-well plate. Hela cells passed through 0, 2.5, 5, 10, 20, 40 g/ml of ACTX-8
After treatm...
Snake venom is a liquid secreted by venomous snakes from their venomous glands. Its main component is toxic protein, accounting for 90% to 95% of the dry weight. There are about 20 kinds of enzymes and toxins. In addition, it also contains some small molecular peptides, amino acids, carbohydrates...
Defibrase is currently approved by the State Food and Drug Administration
For clinical application, it is derived from Agkistrodon acutus (Atracter acutus, known as Ar
Agkistrodon halys Pallas (Gf0, Bilin 6I! D, secreted at the exit of Lisi) ¨ “, mainly used for acute cerebral embolism
The ...